Joel Spolsky's recent essay on Microsoft's API shift is a slam dunk. It's a long article (as blog posts go), but it's a must-read for developers.
Funny enough, I seriously considered moving my development to .NET by writing FeedDemon 1.0 in C#. The C# language itself is very nice, and .NET certainly makes some things a lot easier than Win32. But several existing RSS readers received poor reviews due to their .NET-related memory usage, and requiring the 20MB+ .NET runtime is suicide for most downloadable shareware apps. So, in the end I stuck with Delphi, which I'd used to create both TopStyle and HomeSite. Delphi creates standalone (ie: no runtime) Win32 executables, which for the moment makes it a better choice for shareware.
Oh, and I couldn't help but nod in agreement with this quote from Paul Graham:
"If you want to write desktop software now you do it on Microsoft's terms...and if you manage to write something that takes off, you may find that you were merely doing market research for Microsoft."I'm a one-person shareware company, and I even have to worry about the looming threat of Microsoft entering the same market that my software targets.